Kurzübersicht für BDK_1 (AA 213-239) Antikörper (ABIN652683)
Target
BDK_1
Reaktivität
Human
Wirt
Kaninchen
Klonalität
Polyklonal
Applikation
Flow Cytometry (FACS), Western Blotting (WB)
Klon
RB21729
Bindungsspezifität
AA 213-239
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This BDK_1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-239 amino acids from the Central region of human BDK_1.
Isotyp
Ig Fraction
Applikationshinweise
WB: 1:1000. FC: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Target
BDK_1
Hintergrund
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. BDKRB1 is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.